arGEN-X Launches Innovative Access Program

January 12, 2015

  • Program extends reach of proprietary SIMPLE Antibody™ platform and creates potential for future value creation
  • First collaborations with U.S.-based biotech company active in dyslipidemia and the de Duve Institute in cancer immunotherapy

Breda, the Netherlands / Ghent, Belgium – arGEN-X N.V. (Euronext Brussels: ARGX), a clinical-stage biopharmaceutical company focused on creating and developing differentiated therapeutic antibodies for the treatment of cancer and severe autoimmune diseases, today announced it has initiated its Innovative Access Program, providing its SIMPLE Antibody™ platform to academic centers of excellence and emerging biotech companies through collaboration. The goal of this program is to exploit the proven power of the SIMPLE Antibody™ platform in therapeutic areas complementary to arGEN-X’s strategic focus.

The first Innovative Access Program collaborations are with an unnamed US-based biotechnology company active in the field of dyslipidemia research and with the de Duve Institute (Université Catholique de Louvain - Belgium) in the field of cancer immunotherapy.

“Our SIMPLE Antibody™ technology has far greater therapeutic potential than we can possibly exploit alone,” says Debbie Allen, VP Business Development arGEN-X. “Whilst our strategic focus is on the discovery and development of novel antibody products for the treatment of cancer and severe autoimmune diseases, we are very excited to have launched our Innovative Access Program to extend our reach into multiple therapeutic areas. The Innovative Access Program is configured around flexible, collaborative terms, giving us a strategic position in the future commercial success of developed assets. We see the Innovative Access Program not only as a significant benefit to academia and emerging biotech companies, but also to arGEN-X as a potential driver of value creation.”

arGEN-X Innovative Access Program

The Innovative Access Program leverages the proven power of the SIMPLE Antibody™ platform in creating best-in-class antibodies across multiple therapeutic areas. Through collaboration with academic centers of excellence and emerging biotech companies, arGEN-X will provide access to its antibody discovery technologies and offer technical support and proprietary know-how where needed. Deal structures are designed to be flexible.

Under the terms of the agreement with the U.S.-based biotech company, arGEN-X will provide access to its suite of antibody discovery technologies and offer technical know-how and expertise. In return, arGEN-X will receive a share in the future commercial success of any asset utilizing the arGEN-X technology. Financial details of the transaction were not disclosed.

The collaboration with the de Duve Institute (Université Catholique de Louvain – Belgium) was initiated for the use of the SIMPLE AntibodyTM platform and technical expertise of arGEN-X to validate a novel immune checkpoint target, GARP. arGEN-X will have the rights, following an upcoming predefined milestone, to exercise an option to exclusively in-license GARP-targeting antibodies for further development and commercialization as part of its proprietary product pipeline.