Efgartigimod

Efgartigimod is designed as a first-in-class investigational antibody fragment to target the neonatal Fc receptor (FcRn). Efgartigimod is being evaluated for the treatment of patients with severe autoimmune diseases with confirmed presence of pathogenic immunoglobulin G, IgG autoantibodies, where a severe unmet medical need exists.

Neurology
Hematology / Rheumatology
Dermatology
Nephrology
Indication not disclosed
Program
Clinical trial

Pipeline

Efgartigimod

Target
FcRn
Preclinical
Phase 1
Proof of Concept
Registrational
Commercial
AChR- Generalized Myasthenia Gravis (gMG)
Thyroid Eye Disease (TED)
Bullous Pemphigoid (BP)
Myositis (IMNM, ASyS, DM)
Primary Sjögren’s Syndrome (pSS)
Post-COVID Postural Orthostatic Tachycardia Syndrome (PC-POTS)
Membranous Nephropathy (MN)
Lupus Nephropathy (LN)
ANCA-Associated Vasculitis (AAV)
Antibody Mediated Rejection (AMR)